Tony (Neil A.) Holtzman, a retired physician and medical researcher, is uniquely qualified to write about medical and research errors and their consequences, as he does in Blame. As Professor of Pediatrics, Director of Genetics and Public Policy Studies, and core faculty of the McKusick-Nathans Institute of Genetic Medicine at The John Hopkins School of Medicine, he conducted research on human genetic diseases. His 1989 book, Proceed with Caution examines the implications of DNA analysis on medicine and society. As co-chair of the NIH-Department of Energy Task Force on Genetic Testing, he co-wrote Promoting Safe and Effective Genetic Tests in the United States which lays out criteria for genetic testing in order to reduce diagnostic errors. His short story, The Strange Malady of Alessandro's Uncle, about the consequences of faulty genetic research, was published by BMJ in 2007. He has also published, Adirondack Trilogy—three novels of historical fiction—and over one hundred and fifty scientific papers.

Tony has spent summers in the Adirondacks for over fifty years (with some winter forays, too) and has climbed most of the forty-six peaks over four thousand feet and conoed many rivers and lakes. His interest in the history of the region and the roots of the current conflicts among developers, environmentalists, and the people who live in the region year-round inspired him to write the Adirondack Trilogy. He has participated in writers' workshops at Stanford University, New Mexico State University, and the Adirondack Center for Writing, of which he is a member of the board.